Alan W. Shindel, MD, MAS, discusses the current treatment of erectile dysfunction (ED) with PDE5 inhibitors, as well as the limitations of the currently available drugs for ED patients. He also reviews a number of potential targets for novel ED treatments, including nitric oxide, soluble guanylate cyclase, the RhoA/Rho Kinase/ROCK pathway, and the Sonic Hedgehog protein.
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Alan W. Shindel, MD, MAS, reviews the basic scientific concepts behind low intensity shock wave therapy and the rationale for its use in the management of erectile dysfunction (ED). He discusses existing data from both animal and human models supporting this treatment, as well as the knowledge gaps that must be addressed before adopting it into clinical practice.
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Alan W. Shindel, MD, MAS, explains the current evidence-based recommendations for Peyronie’s disease as described in the 2015 American Urological Association (AUA) guidelines, emphasizing the shared decision-making aspect of these guidelines. He provides an overview of the recommendations regarding the diagnosis of this condition, as well as medical therapy, injections, and surgical repair options.
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Alan W. Shindel, MD, MAS, highlights the fact that, while cisgender lesbian, gay, and bisexual (LGB) people have many similar medical concerns to straight cisgender patients, physicians should exhibit medical professionalism by compentently caring for health risks specific to LGB patients. He reviews urologic concerns germane to this community, like urinary and sexual wellness, as well as quality of life considerations in gay men with prostate cancer.
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Alan W. Shindel, MD, MAS, reviews the framework for evaluation and management of erectile dysfunction set forth in the 2018 American Urological Association (AUA) Guidelines. He discusses how physicians can incorporate these guidelines into their practices while still determining the most effective approach for individual patients through shared decision-making.
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