Current State of Exosome-Based Biomarkers

Johan Skog, PhD, explains how the biology of exosomes and their role in tumor cell growth, angiogenesis, and inhibiting immune cells enables a potential for the use of exosome-based biomarkers in evaluating prostate cancer. He describes evaluating the RNA content of exosomes to provide a more specific analysis of individual patient disease and possibly prevent overdiagnosis and overtreatment of prostate cancer, as well as the ExoDx Prostate (Intelliscore), or EPI, which analyzes urine samples and aims to avoid unnecessary biopsies.

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