A. Lenore Ackerman, MD, PhD

A. Lenore Ackerman, MD, PhD


Los Angeles, California

Dr. A. Lenore Ackerman is Assistant Professor of Surgery, Urology and Pelvic Medicine and Reconstructive Surgery at Cedars-Sinai Medical Center, as well as Adjunct Assistant Professor of Urology in the Department of Surgery, Division of Urology at the David Geffen School of Medicine at UCLA Health. She was born in Los Angeles, CA, but spent her childhood throughout the U.S., from southern California to Maine. After settling in New Haven, CT, she earned her degree in Molecular Biophysics and Biochemistry at Yale University. She later completed her Ph.D. in Immunology at Yale, focusing on molecular mechanisms of antigen presentation in dendritic cells. After realizing a desire to pursue translational medicine, she joined the Medical Scientist Training Program at Yale, receiving her M.D. She completed her internship in General Surgery and began residency in Urology at the University of California, Los Angeles. Under the mentorship of Dr. Larissa Rodriguez, her research during this residency focused on changes in the central nervous system of an animal model due to interstitial cystitis induced by psychological stress. After the completion of residency, she has continued at UCLA as a fellow in Pelvic Medicine and Reconstructive Surgery. Her current research focuses on the role of host-microbe interactions in the etiology of benign lower urinary tract disorders. She now specializes in the treatment of incontinence, voiding dysfunction, and pelvic floor disorders at Cedars-Sinai Medical Center in Los Angeles.


Articles by A. Lenore Ackerman, MD, PhD

Mycoplasma and Ureaplasma Molecular Testing Does Not Correlate with Irritative or Painful Lower Urinary Tract Symptoms

A. Lenore Ackerman, MD, PhD, Director of Research for FPMRS in the Department of Urology at the University of California, Los Angeles, shares data from her research group evaluating diagnostic testing patterns for ureaplasma and mycoplasma and characterizing the associations of these bacteria with irritative lower urinary tract symptoms (LUTS) using molecular detection techniques. Dr. Ackerman explains the context and rationale for the study and reviews how it illustrates Robert Koch’s postulates. She also addresses topics such as how physicians should approach LUTS in culture-negative patients, the significance of the bacteria detected through new sensitive methods, and whether symptoms are proof of infection or if they could be related to something else. Ultimately, she concludes with two main points: that the physician’s focus should be on treating the patient, not on treating a test; and that not all bacteria are bad, as some healthy genitourinary commensal bacteria play an important role in preventing urinary tract infections.

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Recurrent Uncomplicated Urinary Tract Infections in Women: AUA/CUA/SUFU Guideline 2019

Jennifer T. Anger, MD, MPH, Associate Professor of Urology at Cedars-Sinai Medical Center, discusses recurrent uncomplicated urinary tract infections (UTIs) in women. Dr. Anger chairs the AUA committee on guidelines for infections, and she discusses the rationale behind recent changes to recommendations. She outlines how the thinking about recurrent infections has changed over time, and highlights the collateral damage that a one-size-fits-all antibiotic treatment can cause, noting that the new guidelines emphasize treating individual urinary cultures. She goes on to discuss patient profiles, common symptoms, and what the guidelines recommend for initial work-ups as well as treatments. Dr. Anger further delves into ways to prevent or decrease the risk of UTIs with antibiotic prophylaxis, along with the possible risks of doing so.

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Associate Editors

Fred Bartlit, Esq.

Mark A. Moyad, MD, MPH
University of Michigan
Ann Arbor, Michigan