Presentation Overview and Statement of Need

Patterns of care in prostate cancer (PCa) have changed tremendously in the past 20 years, altering the way patients with this tumor present and how they are evaluated before and after diagnosis. With the use of new and combined treatments, the frequency and variety of complications have differed from those previously reported. Advances have been made in PCa imaging, biopsy methodology, in understanding causative factors and disease, in treatment-related quality of life, and in predicting the behavior of individual tumors using risk strata. Despite these advances, no consensus has emerged regarding the optimal treatment for the most common patient with PCa.

A number of educational gaps between recent research in PCa and its integration into professional practice at the international, national, and community levels that were presented and discussed at the 24th annual International Prostate Cancer Update (IPCU 24), held February 19-22, 2014 in Vail, Colorado. The IPCU 24 educational planning committee identified:

•    Current best practices in prevention and screening of prostate cancer
•    Promising therapies, issues, and economic concerns in the treatment of prostate cancer
•    Role of newly available therapies in 2014
•    Emerging treatment options for advanced and castration-resistant PCa

There is a need for oncologists, urologists, and nurses to understand the rationale behind targeted therapy for the treatment of advanced PCa, and how trial entry could improve the efficacy of drugs and decrease the toxicity.
This activity seeks to educate urologists and other healthcare professionals about the latest advances in the prevention, screening, and treatment of PCa, and is a highlights of selected presentation topics presented in February 2014 in Vail, Colorado.


Grand Rounds in Urology


Keywords: prostate cancer, blood tests, urine tests, SNP, gene expression assays, MRI, biomarkers, AUA Guidelines, targeted biopsy, standard biopsy, template biopsy, testosterone replacement, adjuvant radiotherapy, salvage radiotherapy, radiation toxicity, PSA recurrence, molecular targeting, PSMA imaging agents, focal therapy, androgen deprivation therapy, GnRH antagonists, radiosurgery, CyberKnife, optical spectroscopy, PET imaging, salvage cryotherapy, salvage prostatectomy, ADT, novel hormonal therapies, radiopharmaceuticals, mCRPC

How to cite: Crawford, E. David, Et Al. “Highlights from the 24th International Prostate Cancer Update.” Grand Rounds in Urology. June 1, 2014. Accessed May 2022.


Medical Editor:

E. David Crawford, MD
University of Colorado Denver
Aurora, Colorado


Alan W. Partin, MD, PhD
Johns Hopkins Medical Institutions
Baltimore, Maryland

M. Scott Lucia, MD
University of Colorado Denver
Aurora, Colorado

Peter F. A. Mulders, MD, PhD
Radboud University Medical Center
Nijmegen, The Netherlands

Daniel P. Mulders, MD
Yale Cancer Center
New Haven, Connecticut

Neal D. Shore, MD
Atlantic Urology Clinics, LLC
Myrtle Beach, South Carolina

Leonard G. Gomella, MD
Thomas Jefferson University
Philadelphia, Pennsylvania





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