Raoul S. Concepcion, MD, FACS, provides an overview of the epidemiology of upper tract urothelial carcinoma (UTUC). He discusses the most recent efforts in improving management for the disease, particularly focusing on neoadjuvant chemotherapy when treating high-grade tumors and nonsurgical ways to combat low-grade UTUC.
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Raoul S. Concepcion, MD, FACS, emphasizes the need for more effective biomarkers when determining adequate treatment for patients with castrate-resistant prostate cancer (CRPC). Concurrently, he compares the findings of studies exploring various options, including the AR-V7 splice variant.
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Raoul S. Concepcion, MD, FACS, provides a brief overview of the background, incidence, and epidemiology of upper tract urothelial carcinoma (UTUC). He then discusses indications for nephroureterectomy with a cuff of bladder and possible methods for management that would be less invasive for low-grade UTUC patients.
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Raoul S. Concepcion, MD, FACS, discusses the challenge of managing upper tract urothelial cancer (UTUC) while avoiding overtreatment. Although nephroureterectomy is an appropriate treatment for high grade tumors, urologists should utilize localized therapy and avoid surgery in low-grade UTUC.
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Raoul S. Concepcion, MD, summarizes the mechanism of action behind the immune response to cancer. He also provides an update on the current and emerging immunotherapies for cancer treatment, including vaccines, checkpoint inhibitors, CAR T-cell therapies, viral vectors, and adoptive cell therapy.
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