L. Michael Glodé, MD, FACP, presented “The Case for Standard Imaging” during the Perspectives in Urology: Point Counterpoint 2020 virtual conference in November 2020.
How to cite: Glodé, L. Michael. “The Case for Standard Imaging” November 2020. Accessed Dec 2024. https://dev.grandroundsinurology.com/the-case-for-standard-imaging/
The Case for Standard Imaging – Summary
L. Michael Glodé, MD, FACP, Professor Emeritus of Medical Oncology and the former Robert Rifkin Chair for Prostate Cancer Research at the University of Colorado Cancer Center in Aurora, Colorado, presents the case for standard imaging over second-generation technology in urologic oncology. One compelling reason to consider standard imaging like bone scans is the extensive data that have culminated in criteria on when to order routine scans such as these. Advanced imaging currently lacks both the wealth of data and scanning criteria, leading to questions about the frequency of false positives and false negatives and whether radiologist training is consistent. Dr. Glodé observes that we understand the limitations of conventional imaging, adding that there is insufficient data to make any such determination about the accuracy of second-generation scans. Since trials studying second-generation anti-androgens over the last few years have employed conventional imaging, Dr. Glodé suggests the more sensitive second-generation imaging could potentially deny patients with now-visible metastases access to some drugs based on eligibility criteria. The cost of newer imaging techniques is also prohibitive, especially if they do not replace current scans or change approaches to treatment. He concludes that the level 1 evidence on treatment of non-metastatic castration-resistant prostate cancer using conventional scans weighed against the cost of second-generation scans and the potential for inconsistent application of newer technology suggest that doctors should better utilize current standard imaging.
Click here for the pro-next generation imaging perspective of this point-counterpoint series.
About the Perspectives in Urology: Point Counterpoint 2020 virtual conference:
Presented by Program Chair and Grand Rounds in Urology Editor-in-Chief E. David Crawford, MD, as well as Program Co-Chair Dan Theodorescu, MD, PhD, this virtual conference brought together leading experts in urology, medical oncology, and radiation oncology to discuss and debate the latest topics in genitourinary cancers, primarily prostate cancer and bladder cancer. This two-day interactive conference offered topical lectures, pro/con debates, interesting-case presentations, interactive panel discussions, and interactive audience and faculty networking. A focus on prostate cancer was given on Wednesday, November 11th, with a focus on bladder cancer given on Thursday, November 12th.
ABOUT THE AUTHOR
Dr. Glodé is Professor Emeritus of Medical Oncology and the former Robert Rifkin Chair for Prostate Cancer Research at the University of Colorado Cancer Center in Aurora, Colorado. He was the first board-certified medical oncologist at the University of Colorado, joining the faculty after training at the Dana-Farber Cancer Institute in Boston. Dr. Glodé’s research has been clinically focused on prostate cancer for many years. He headed the initial research on leuprolide, leading to its approval. He has also led efforts to evaluate a natural product, silibinin, as a preventive or therapeutic agent. He has been an investigator on more than 30 clinical trials, including the PI position for one of the largest adjuvant trials in prostate cancer, SWOG 9921. Dr. Glodé has received numerous teaching awards and founded the AACR course “Molecular Biology for Clinical Oncologists.” He has also served as Founding Editor of the ASCO website, as well as Chair of ASCO’s Integrated Media and Technology and Cancer Education Committees. He is the author of prost8blog, a blog intended to help prostate cancer patients and their families.
